|
IMAGE MAP
With this image map, it is possible to address individual illustrations and to use the brief characterizations as a guide to the selection. On the
other hand, the reader might wish to scroll the Pictorials 1, 1a, 2, 3, and 4 page by page to initially gain an appreciation for the histology of the lesion and in preparation for the Discussion and the Conclusion (see
NAVIGATIONAL GUIDES in the left margin).
PICTORIAL 1 (low magnifications):
P1-1a: overall view; halo nevus-like pattern: P1-1b: halo nevus-like pattern, higher magnification: P1-2a: overall view; different section: P1-2b: area showing preponderance of epithelioid cells with only scattered nests of pigmented, small nevus cells:
PICTORIAL 1A (comparisons with another example of a halo
nevus-like variant and comments on the nature of halo nevus-like phenomena):
P1a-1: halo nevus-like lesion (not problem case); spindle cells in junctional patterns; atypia
of halo nevus-like type in dermal component: P1a-2: junctional patterns and a dermal nest; cells in dermal nest show atypia of halo nevus-like type: P1a-3: focal regression; senescent phase of cell mediated immunity: P1a-4: drawing of
life history of cell mediated immune reaction of lichen planus-like type: P1a-5: fibrous inlay of lytic defect in epidermal domain of lichen
planus-like reaction: P1a-6: focal senescence in lichen planus-like reaction with entrapment of numerous colloid bodies in newly formed fibrous tissue
PICTORIAL 2 (intermediate magnifications):
P2-1: lentiginous and junctional, as well as dermal, components with much of the latter deviating
cytologically from common nevus cells: deviant epithelioid cells of the dermis are arranged in ill-defined fascicular patterns; P2-2: halo
nevus-like patterns but cytologically deviant with prominence of epithelioid cells, particularly in dermal component: P2-3: lentiginous and
junctional components; fascicles of common nevus cells and fascicles of epithelioid cells (in common nevus cell-like fascicular patterns) intimately associated: P2-4: same general area, higher magnification:
PICTORIAL 3 (higher magnifications with variations of
epithelioid cell patterns and with pigmented, small “nevus cell” patterns {new growth = dysplastic epithelioid cell melanocytoma):
P3-1: general lack of continuity between junctional component and dermal, epithelioid
component: P3-2: halo nevus-like patterns but ambiguous cytologic and fascicular patterns: P3-3: remarkably uniform and bland, epithelioid cytologic features: P3-4:
lentiginous and junctional component of pigmented spindle cells; intermingling of fascicles of epithelioid cells and fascicles of common nevus cells; cytolytic (halo nevus-like) phenomena with loose lymphoid
infiltrates: P3-5: fascicles of pigmented, small nevus cells; fascicles of bland epithelioid, round cells; halo nevus-like (cytolytic)
phenomena:
PICTORIAL 4 (high magnifications; pigmented, small “nevus cells”
and dysplastic epithelioid cell melanocytoma; halo nevus-like phenomena):
P4-1: lentiginous and compound, premalignant dysplasia-like patterns; epithelioid cells in dermal
component; halo nevus-like (cytolytic) phenomena: P4-2: junctional components; pigmented, small nevus cell components; epithelioid
components; halo nevus-like (cytolytic) phenomena: P4-3: epithelioid components; pigmented, small nevus cell-like component; halo nevus-like
(cytolytic) phenomena; patterns of regression (sclerosis and entrapment of epithelioid cells): P4-4: central nests of pigmented, small nevus
cells; epithelioid cells in ensheathing patterns about nests of pigmented, small nevus cells:
PICTORIAL 5:
P5-1: basic features of near-neoplasia of halo nevus-like type
|
